By David E. Schteingart (auth.), Gary D. Hammer, Tobias Else (eds.)
This first version of the textbook “Adrenocortical Carcinoma: simple Sciences and medical thoughts” presents a concise compilation of correct information advancing our present figuring out of this infrequent melanoma. Chapters are devoted to numerous points of either the elemental biology and the scientific technology with regards to adrenocortical carcinoma (ACC). specialist clinicians introduce the reader to present state of the art scientific care of sufferers with ACC. As a substantial physique of information on ACC has accrued over the past many years, professional scientists have authored extra sections that function a reference resource for the skilled researcher in addition to an creation for the trainee within the laboratory or medical institution. scientific themes span the epidemiology, analysis and treatment of ACC. clinical issues parts span the pathology and pathophysiology of ACC with a unique specialise in experimental types of adrenocortical tumors and up to date advances within the genetic features and signaling pathways in ACC. The content material of this ebook used to be compiled and edited with the reason of facilitating the interpretation of data into destiny diagnostic and healing instruments that might finally increase sufferer care.
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Extra info for Adrenocortical Carcinoma: Basic Science and Clinical Concepts
Medicine 44: 37–39 19. Lanigan D et al (1993) A feminizing adrenocortical carcinoma presenting with gynaecomastia. Postgrad Med J 69(812):481–483 20. Allolio B et al (2004) Management of adrenocortical carcinoma. Clin Endocrinol (Oxf) 60:273–287 21. Seccia TM et al (2005) Aldosterone-producing adrenocortical carcinoma: an unusual cause of Conn’s syndrome with an ominous clinical course. Endocr Relat Cancer 12(1):149–159 22. Barzon L et al (2005) Shift from Conn’s syndrome to Cushing’s syndrome in a recurrent adrenocortical carcinoma.
Chemotherapy for metastatic disease) . In this setting, adrenal biopsy, either as FNA cytology or as adrenal cut biopsy, will give a sensitivity and specificity of more than 80% and an overall accuracy of 90% . Some researchers, however, are more enthusiastic concerning the use of image-guided FNA cytology for the characterization of adrenal masses. In 34 consecutive patients, image-guided FNA cytology using spinal-type narrow gauge needles prior to further procedures was used . 3%, 100%, and 100% superior to CT or MRI imaging.
Cancer 88(4):711–736 14. Bilimoria KY et al (2008) Adrenocortical carcinoma in the United States: treatment utilization and prognostic factors. Cancer 113(11):3130–3136 15. Fassnacht M, Allolio B (2009) Clinical management of adrenocortical carcinoma. Best Pract Res Clin Endocrinol Metab 23(2):273–289 16. Fassnacht M et al (2009) Limited prognostic value of the 2004 International Union Against Cancer staging classification for adrenocortical carcinoma: proposal for a revised TNM classification.